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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP45
All Species:
12.73
Human Site:
S390
Identified Species:
21.54
UniProt:
Q70EL2
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q70EL2
NP_001073950
814
91733
S390
P
I
I
E
E
R
V
S
K
P
L
L
W
G
R
Chimpanzee
Pan troglodytes
XP_001139771
814
91702
S390
P
I
I
E
E
R
V
S
K
P
L
L
W
G
R
Rhesus Macaque
Macaca mulatta
XP_001085248
815
91829
S391
P
I
I
E
E
R
V
S
K
P
L
L
L
G
R
Dog
Lupus familis
XP_539054
796
87704
L382
D
P
F
I
D
I
S
L
P
I
I
E
E
R
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8K387
813
90343
R389
S
L
P
I
I
E
E
R
V
S
K
P
V
L
L
Rat
Rattus norvegicus
Q2KJ09
826
93743
G394
P
V
L
D
D
Q
S
G
K
K
N
I
N
D
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506389
799
87920
S384
K
E
P
F
L
D
L
S
L
P
I
I
E
E
R
Chicken
Gallus gallus
O57429
357
40913
Frog
Xenopus laevis
Q6PAW2
901
101274
V395
P
V
L
D
D
L
I
V
K
K
N
S
K
S
T
Zebra Danio
Brachydanio rerio
A8HAL1
815
90431
P401
M
F
L
D
L
S
L
P
V
A
D
E
A
Y
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121285
844
94413
Q404
P
V
M
A
D
K
P
Q
P
P
V
L
K
K
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790411
1122
123641
S418
P
I
T
E
A
K
G
S
K
R
N
L
S
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FPT5
1083
120752
V495
A
V
I
D
E
A
Q
V
C
G
C
P
D
L
E
Baker's Yeast
Sacchar. cerevisiae
P50102
471
53605
M59
I
N
S
G
A
T
F
M
C
L
Q
C
G
F
C
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
94.4
72.2
N.A.
77.4
38.7
N.A.
63.7
20.1
38.5
38
N.A.
N.A.
29.3
N.A.
29.9
Protein Similarity:
100
99.7
96.6
81.5
N.A.
85.3
59.6
N.A.
75.5
29.7
56.4
56.6
N.A.
N.A.
49.1
N.A.
45.3
P-Site Identity:
100
100
93.3
0
N.A.
0
13.3
N.A.
20
0
13.3
6.6
N.A.
N.A.
20
N.A.
40
P-Site Similarity:
100
100
93.3
13.3
N.A.
6.6
60
N.A.
40
0
46.6
26.6
N.A.
N.A.
53.3
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.3
20.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.6
35.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
15
8
0
0
0
8
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
15
0
8
8
0
0
8
% C
% Asp:
8
0
0
29
29
8
0
0
0
0
8
0
8
8
0
% D
% Glu:
0
8
0
29
29
8
8
0
0
0
0
15
15
8
8
% E
% Phe:
0
8
8
8
0
0
8
0
0
0
0
0
0
8
0
% F
% Gly:
0
0
0
8
0
0
8
8
0
8
0
0
8
22
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
29
29
15
8
8
8
0
0
8
15
15
0
0
0
% I
% Lys:
8
0
0
0
0
15
0
0
43
15
8
0
15
8
8
% K
% Leu:
0
8
22
0
15
8
15
8
8
8
22
36
8
15
8
% L
% Met:
8
0
8
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
0
0
22
0
8
0
8
% N
% Pro:
50
8
15
0
0
0
8
8
15
36
0
15
0
0
0
% P
% Gln:
0
0
0
0
0
8
8
8
0
0
8
0
0
0
0
% Q
% Arg:
0
0
0
0
0
22
0
8
0
8
0
0
0
8
36
% R
% Ser:
8
0
8
0
0
8
15
36
0
8
0
8
8
15
8
% S
% Thr:
0
0
8
0
0
8
0
0
0
0
0
0
0
0
8
% T
% Val:
0
29
0
0
0
0
22
15
15
0
8
0
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
15
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _